Associate Oligonucleotides Analytics (m/w/d)

About the role

F. Hoffmann-La Roche is looking for an Associate Oligonucleotides Analytics (m/w/d) in Basel, recruited through a Swiss personnel service company. The role sits in Analytical Research and Development for synthetic molecules within Pharma Technical Development, which develops resource- and cost-efficient analytical methods using techniques such as HPLC, gas or ion chromatography and mass spectrometry. The aim is to build a robust control strategy to release products for clinical trials and commercial supply.

Key responsibilities

• Perform routine measurements for oligonucleotides, mainly HPLC with UV and/or single quad MS detection
• Plan, execute and document experiments collaboratively in a team of five associates
• Use chromatographic data systems such as Empower or OpenLab to control analytical instruments
• Evaluate data with Genedata or Oligo Analysis Accelerator
• Develop, improve and validate analytical methods for the quality assessment of oligonucleotides
• Ensure compliance with GxP guidelines and relevant SOPs

Required profile

• Vocational scientific qualification (e.g. apprenticeship, laboratory technician, Chemielaborant); no university degree, master's or PhD required
• 2 to 3 years of experience in the pharmaceutical industry, focused on analytical development for oligonucleotides or peptides
• Strong hands-on expertise with HPLC, MS and ideally LC-MS
• Excellent quality mindset, attention to detail and ability to adapt quickly to new tools and agile ways of working
• Confident communication in English; German is beneficial

Required skills

• Hands-on experience with analytical instrumentation and techniques such as HPLC and MS
• Knowledge of GxP requirements across clinical phases
• Strong knowledge of LC-MS applications and instruments is a plus
• Experience with large molecules/biologics analytics is an advantage

Working hours are standard 40 hours per week, with up to 10% remote work. Applications are sent by e-mail to the recruitment agency with CV, certificates and training certificates.