Internship in Manufacturing Science and Technology (12 months)

About the role

Roche is offering a 12-month internship in Manufacturing Science and Technology in Basel. You will support MSAT process performance on a DMAc peroxide evaluation project, working on analytical method comparability, an oxidation impact study, QC method transfer and handover documentation.

Key responsibilities

• Analytical method comparability: determine and validate the repeatability of a DMAc peroxide concentration dilution series using NMR.
• Oxidation impact study: analyze existing study data to design an experimental plan and help execute the scale-down model to assess methionine 255 oxidation under Kadcyla manufacturing conditions.
• QC method transfer: use findings from the oxidation study to define a formal peroxide threshold and support its transfer to Quality Control.
• Final handover: provide study plans, final reports and SOP-compliant documentation covering the whole DMAc peroxide evaluation.
• Support digitalization initiatives, such as implementing a PM parameter report.

Required profile

• Master's degree completed within the last 12 months in biochemistry, biotechnology or chemical engineering, or currently enrolled in a Master's programme.
• Fluent English and German.
• Non-EU/-EFTA nationals must provide a university confirmation that the internship is mandatory for their studies.

Required skills

• Familiarity with analytical chemistry techniques, including NMR and quantitative assays.
• Knowledge of protein degradation mechanisms such as oxidation.