Director, Medical Affairs International

About the role

The Director, Medical Affairs International will lead the strategic and operational medical affairs activities for Alnylam’s RNA therapeutic portfolio across multiple countries outside the United States. Reporting to global medical leadership, the role partners with affiliate teams, commercial, market access and regulatory functions to ensure evidence‑based, patient‑focused initiatives.

Key responsibilities

• Develop and execute regional medical affairs strategy for TTR programs in the International region.
• Act as the medical lead on cross‑functional regional teams, collaborating with commercial, regulatory, market access and HEOR colleagues.
• Support affiliate medical teams with launch readiness and alignment of local and regional activities.
• Identify data gaps and drive regional data generation plans, including real‑world evidence, investigator‑initiated studies and registries.
• Provide scientific input to regional and global brand and launch strategies.
• Engage key opinion leaders through advisory boards, symposia and medical education events.
• Ensure compliance with global and local regulatory and ethical standards.
• Train affiliate and regional teams on RNA therapeutics and disease‑specific science.

Required profile

• Medical Doctor (M.D.) and/or PhD or equivalent academic healthcare professional.
• Minimum 3 years experience in Medical Affairs within a pharmaceutical or biotechnology company, preferably in global or regional roles.
• Proven strategic thinking, problem‑solving and decision‑making abilities, with launch experience.
• Excellent written and verbal communication skills.
• Ability to work independently, travel ≥25 % of the time and operate in a matrix organization.

Required skills

• In‑depth knowledge of RNA therapeutics and related disease areas.
• Understanding of regional regulatory and pricing & reimbursement processes.
• Experience with real‑world evidence generation and investigator‑initiated studies.