Senior Principal Scientist – Soluble Biomarkers

About the role

Novartis is seeking a Senior Principal Scientist / Associate Director to lead exploratory soluble biomarker strategies within Molecular & Cellular Sciences. The role combines biology, technology, and clinical development to deliver innovative biomarker solutions that support smarter decisions and better patient outcomes.

Key responsibilities

• Lead a team developing, validating, and implementing soluble biomarker assays using LC‑MS and immunoassay platforms across the portfolio.
• Serve as subject‑matter expert for LC‑MS, ELISA, MSD, NULISA, and Ella technologies, overseeing laboratory operations and resource planning.
• Provide hands‑on technical leadership for method development, validation, sample analysis, and result delivery.
• Drive biomarker assay activities for clinical studies, both internal and outsourced.
• Analyze complex data, translate findings into actionable recommendations, and represent Novartis in scientific publications and conferences.

Required profile

• PhD with 5+ years (or MSc with 8+ years) of industry experience in biomarker development or translational research.
• Previous people‑leadership experience at Associate Director level.
• Proven scientific leadership, cross‑functional collaboration, and strong communication skills.

Required skills

• LC‑MS assay development and validation.
• Immunoassay platforms: ELISA, MSD, NULISA, Ella.
• Soluble biomarker assay development and clinical implementation.

What we offer

• Competitive base salary CHF 122,500 – CHF 227,500 per year.
• Performance‑based bonus, long‑term equity awards, and comprehensive benefits including insurance, retirement plans, wellbeing resources, flexible hybrid working, and 14 weeks paid parental leave.